The product CSB-E12756h manufactured by CUSABIO is a solid-phase sandwich ELISA kit that allows for the quantitative determination of anti-Mullerian hormone (AMH) in the samples, including serum, plasma, and tissue homogenates. This human AMH ELISA kit specifically recognizes the human AMH. It has been quality validated through multiple criteria, including sensitivity, specificity, precision, and lot-to-lot consistency. More details are described in the product instructions.

Samples and standards are respectively pipetted into the appropriate micro ELISA plate wells pre-coated with anti-human AMH antibody. The Biotin-labeled AMH antibody is added to form a sandwich of immune complexes. HRP-avidin and TMB substrate are successively added, and the solution turns blue. The blue turns yellow after the addition of the stop solution. The color intensity is proportional to the AMH content in the sample.

AMH is a homodimeric glycoprotein belonging to the transforming growth factor-beta family. AMH gets its name because of its role in the regression of the Mullerian ducts during male sex differentiation. AMH is produced by granulosa cells of growing ovarian antral follicles. Serum AMH is the preferred ovarian reserve marker and also can serve as a useful biomarker to indicate the risk of menstrual disturbance due to polycystic ovarian syndrome (PCOS). AMH is regarded as a neuroendocrine regulator of fertility based on AMH receptors outside of the gonads and their ability to regulate both gonadotropic cells of the anterior pituitary and the hypothalamu