The product CSB-E08000h is a ready-to-use microwell, strip plate ELISA Kit for quantitative analysis of human basic fibroblast growth factor (bFGF) in biological samples, including serum, plasma, cell culture supernates, and tissue homogenates. Based on the Sandwich-ELISA technique in combination with the enzyme-substrate chromogenic reaction, the bFGF levels can be calculated according to the standard curve.

This Human bFGF ELISA Kit has been verified by multiple tests with high sensitivity, strong specificity, precision less than 10%, good linearity, high recovery, and lot-to-lot consistency.

bFGF, also known as FGF2 or FGF-β, is an essential mitogen for fibroblasts and belongs to the FGF family. Like other FGF family members, FGF2 has broad mitogenic and cell survival activities. It displays broad biological functions, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It is also evident that FGF2 plays a crucial role in cell proliferation, differentiation, migration, and apoptosis in airway structural cells, contributing to epithelial repair, airway smooth muscle cells (ASMCs) hyperplasia, and vascular remodeling. Over the past decade, FGF2 has been involved in learning and memory, as well as in several neuropsychiatric disorders, including anxiety, stress, depression, and drug addiction. FGF2 is also important for bone development, maintenance, and fracture healing.