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Human soluble cluster of differentiation 14,sCD14 ELISA Kit

Product Details

Description

This ELISA kit is used for quantitative detection of a human soluble cluster of differentiation 14 (sCD14), establishing normal detection range and validation of antibody array results. CD14 is a pattern-recognition receptor and exists in two different forms: GPI-anchored membrane CD14 (mCD14) and liver-derived serum soluble CD14. sCD14 is an acute-phase protein upregulated significantly during sepsis but is also found in normal serum at microgram concentrations. CD14 plays an important role in the phagocytic clearance of apoptotic cells and the reactivation and immune recognition of microbial cell wall components from Gran-positive and Gram-negative bacteria. sCD14 can transfer the LPS to the TLR4/MD-2 complex, eliciting a cascade of inflammatory signaling and TLR4 endocytosis. Based on the Sandwich-ELISA principle and enzyme-substrate chromogenic reaction property, the users can measure the content of human CD14 in serum, plasma, cell culture supernates, tissue homogenates, or urine....Read more

Target Name

CD14 molecule

Alternative Names

CD 14 ELISA Kit; CD_antigen=CD14 ELISA Kit; CD14 ELISA Kit; CD14 antigen ELISA Kit; CD14 molecule ELISA Kit; CD14_HUMAN ELISA Kit; LPS-R ELISA Kit; Mo2 ELISA Kit; Monocyte differentiation antigen CD14 ELISA Kit; Monocyte differentiation antigen CD14 urinary form ELISA Kit; Monocyte differentiation antigen CD14; membrane-bound form ELISA Kit; Myeloid cell specific leucine rich glycoprotein ELISA Kit; Myeloid cell-specific leucine-rich glycoprotein ELISA Kit

Abbreviation

CD14

Uniprot No.

P08571

Species

Homo sapiens (Human)

Sample Types

serum, plasma, cell culture supernates, tissue homogenates, urine

Detection Range

0.234 ng/mL-15 ng/mL

Sensitivity

0.229 ng/mL

Assay Time

1-5h

Sample Volume

50-100ul

Detection Wavelength

450 nm

Research Area

Immunology

Assay Principle

quantitative

Measurement

Sandwich

Storage

Store at 2-8°C. Please refer to protocol.