Rat Immunoglobulin E,IgE ELISA Kit

The product CSB-E07984r is a ready-to-use microwell, strip plate ELISA Kit for quantitative analysis of rat immunoglobulin E(IgE) in serum and plasma. The detection mechanism of this kit is based on the Sandwich-ELISA technique. IgE in the samples or standards is sandwiched between pre-coated IgE antibody and Biotin-conjugated IgE antibody. The IgE/pre-coated IgE antibody/Biotin-conjugated IgE antibody complex is labeled by HRP and then occurs a chromogenic reaction after the addition of the TMB solution. The color intensity is positively related to the IgE in the samples. This kit has undergone rigorous quality tests in multiple parameters, including specificity, sensitivity, precision, linearity, recovery, and lot-to-lot consistency. More details are described in the product instructions.

IgE is a group of antibodies produced by the immune system when overreacting to an allergen. IgE travels to cells including mast cells and basophils and then binds to the Fc receptors on the surface of these cells, inducing these cells to release chemicals and resulting in an allergic reaction. It commonly triggers symptoms in the skin, nose, throat, or lungs. The levels of IgE are normally very low in the blood but get higher when the body is fighting against a parasitic infection or with some immune system conditions. Each type of IgE has a specific "radar" for each type of allergen. That's why some people are only allergic to pollen, while others have allergic reactions to multiple allergens due to more kinds of IgE antibodies present in their bodies.